We provide our clients with imaging assays to accelerate their drug development programs.

High Resolution 3D Imaging


Studies are performed with our state-of-the-art imaging technology that provides histological detail over whole organs, and which has proven itself in numerous large scale research projects (Oh, et al. Nature 2014, Okano et al. Neuron 2016)



We specialize in studies involving tens to hundreds of samples so we can provide clients with the necessary statistical power and reliability required to move a research program forward.

Automated Data Pipelines


3D histology can easily generate terabytes of data for a single drug  study. Our cloud-based analysis services can process large volumes of data and quickly provide quantitative answers.

About TissueMetrics


TissueMetrics is a Boston based biotech contract research organization (CRO) that works with pharmaceutical, biotech, and academic organizations to help meet the challenges of high-throughput 3D histology and whole organ studies. TissueMetrics is made up of experts who have been working in the field of tissue imaging and analysis for 25 years and understand what is needed to move your research program forward. Customers can prepare samples on their own and send us fixed tissues, which we can image and process through our standard assays. In addition, we also work with clients to develop custom assays and are capable of handling entire studies from animal husbandry through tissue labeling and image analysis.

Study Design

Tissue samples are prepared  for imaging.


Samples are evaluated by our imaging pipeline.


Datasets are analyzed by standard or custom data pipelines.  

Standard & Custom Assays

Below we list representative standard assays. For these assays we can provide high confidence in the success of your given study as we have identified and removed many of the pitfalls associated with setting up a new study. We also routinely work closely with clients to develop custom assays for their specific drug development programs.


TissueMetrics Consultation

At TissueMetrics, we work closely with all of our clients to help them make the new discoveries they are after. We are here to help you navigate the critical decisions that will make your experiment a success.

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